Methods for assessment of microcirculation

To date, many methods have entered rheumatological practice in order to evaluate more accurately the microcirculation. Most of them are non-invasive or minimally invasive, easily accessible, providing different information depending on specifics study.
 Over years, some (such as chromametry and volumetry) lost their routine application acquired rather historical significance, while others become an integral part armentarium. An example this is video capillaroscopy, which, through its dynamic development over last 20 has evolved knowledge changes microcirculation systemic sclerosis, well other connective tissue diseases. The expansion area led updating classification criteria for allowing addition capillaroscopic recognized by European League against Rheumatism (EULAR).
 Another important indication performing capillaroscopy differentiation primary from secondary Raynaud's phenomenon. Laser Doppler perfusion imaging also used detect phenomenon distinguish whether reduced blood flow due autoimmune disease. Thermography a helpful role diagnosing phenomenon, but unlike two methods, it much limited lack discriminative ability nutritional thermoregulatory flow, which leads erroneous conclusions pathological conditions.
 Venous occlusive plethysmography one "gold standards" assessment vascular function health disease accurate, reproducible convenient method assess effect new vasoactive drugs. However, everyday quite limited.